Delong Bao, Yong Xia

(Department of Neonatology, Affiliated Children's Hospital of Chongqing Medical University)

Abstract：

Necrotizing enterocolitis (NEC) is a leading cause of death from gastrointestinal disease in premature and low-birth-weight infants. Early detection of severely ischemic or necrotic bowel before perforation is rather difficult. New techniques including multi-omics contribute to better understanding its underlying mechanisms and discovering differe categories of biomarkers. Combination of clinical metrics such as seven components of metabolic derangement (CMD) may provide accurate assessment of its severity. Implementation of quality improvement initiatives including breast milk feeding actually lowers its incidence.

Key Words：

enterocolitis; genomics; infant; newborn