Yazhi Zhao, Buyan Lu

(The First Clinical School of Yan'an University)

Abstract：

Vulnerable plaques in coronary arteries are prone to rupture, leading to thrombotic occlusion of the coronary arteries, which is an important pathogenic mechanism that causes major cardiovascular adverse events. Plaque rupture and plaque erosion are the two main phenotypes of vulnerable plaques, with different clinical characteristics and treatment strategies. Patients with plaque erosion have a smaller range of myocardial infarction and a better prognosis. The integrated application of multimodal intravascular imaging techniques can help evaluate plaque instability, improve diagnostic accuracy, and enhance treatment outcomes. This article reviews the clinical research progress of vulnerable coronary artery plaques in recent years.

Key Words：

vulnerable plaques; major cardiovascular adverse events; Intravascular imaging techniques