Yiheng Liu, Mingsheng Huang

(Tongji Medical College)

Abstract：

Complement C1q/tumor necrosis factor⁃related protein( CTRP) is a highly conserved lipocalin paralog with similar structure roles in cardiovascular diseases,such as atherosclerosis, ischemic cardiomyopathy, and hypertension.Numerous studies have shown that among the complement CTRP family, CTRP1 and CTRP5 promote the development of atherosclerosis, and CTRP3, CTRP6, CTRP9, CTRP12 , CTRP13 , and CTRP15 inhibit atherosclerotic progression. This article reviews recent advances on the role in atherosclerosis.

Key Words：

C1q/tumor necrosis factor⁃related protein;coronary heart disease;atherosclerosis