Zihe Wang, Mingli Huang

(Graduate School of Qinghai University)

Abstract：

Mesenchymal stem cells are pluripotent stromal cells that have the potential to differentiate into a variety of cells. They mainly exert anti-apoptotic, anti-inflammatory, regulating autophagy and promoting endothelial cells and angiogenesis by secreting exosomes (EXO). Studies have shown that autophagy is a process of cell catabolism, which can maintain cell homeostasis and survival, and repair damaged cardiomyocytes. This article mainly reviews the research status of mesenchymal stem cell-derived exosomes (MSCs-EXO) involved in cardiovascular diseases by regulating autophagy, in order to provide new ideas for the treatment of cardiovascular diseases.

Key Words：

cardiovascular diseases; Mesenchymal stem cell; exosomes; autophagy; review