杨 霞 冯 璐 翟晓松 田 敏 郭 振*
潍坊科技学院贾思勰农学院
摘要(Abstract):
胶原蛋白具有优异的生物学性能,已成为生物医学领域应用的重要生物材料,但由于其材料机械强度方面的缺陷在应用中受到限制。本文综述了胶原蛋白的分子结构、其生物材料的机械性能和热稳定性。总结了该领域的最新研究成果,以期为新型胶原基生物材料的开发和改进提供参考和启发。
关键词(KeyWords):
胶原蛋白;生物材料;机械性能;热稳定性
参考文献(References):
[1]Launey M E , Buehler M J , Ritchie R O .On the Mecha nistic Origins of Toughness in Bone[J].Annual Review of Materials Research, 2010, 40(1):25-53.
[2]Liao W , LiuY , XiaG ,et al.Characterization of three‐spot seahorse (Hippocampus trimaculatus) skin collagen and its fibrillar gel reinforced by EDC: A comparative study [J].Journal of Food Biochemistry, 2017:e12391.
[3]Anna S ,M L D ,Zhuning W , et al.The Collagen Supraf amily: From Biosynthesis to Advanced Biomaterial Development.[J]. Advanced materials (Deerfield Beach, Fla.),2018,31(1):e1 801651.
[4]Gobeaux F ,Mosser G ,Anglo A ,et al.Fibrillogenesis in Dense Collagen Solutions: A Physicochemical Study[J].Journal of Molecular Biology,2007,376(5):1509-1522.
[5]El-Rashidy A A ,Gad A ,Abu-Hussein G E A , et al. C rohm e im s in c ia l lota in cd asb ) iolo fi g s i h ca s lc e a v le alcu o a l t l ia o gn en of [ E J g ] y .p I tn ia ten rnN a i t l ie onT a il la J p o iu a r( nal O o r feB o ic oh l ogical Macromolecules,2015,79618-626.
[6]Kirkness W M ,Lehmann K ,Forde R N .Mechanics and structural stability of the collagen triple helix[J].Current Opinion in Chemical Biology,2019,5398-105.
[7]Ricard-Blum S ,Ruggiero F ,Rest M V D .The Collagen Superfamily[J].Topics in current chemistry, 2005, 247:35-84.