Welcome To  NEM   

Journals(Abstract)

慢性阻塞性肺病伴睡眠障碍的研究进展

杨禹康

赣南医科大学第一附属医院

摘要(Abstract):

慢性阻塞性肺病(ChronicObstructivePulmonaryDisease,COPD)作为全球高发的慢性呼吸系统疾病,常与睡眠障碍共病,显著加重患者病情负担、损害认知功能及身心健康,并增加心血管事件与全因死亡风险。本文系统梳理COPD伴睡眠障碍的临床现状,深入剖析两者间的病理机制与双向作用关系,全面综述当前干预策略与研究前沿,结合近年临床调查、机制探索及干预研究成果(含系统评价、meta分析及中西医结合研究),明确共病的患病率特征、风险预测因子及治疗新方向,为临床诊疗优化与科研深化提供参考。


关键词(KeyWords):

慢性阻塞性肺病;睡眠障碍;病理机制;干预策略;认知功能


参考文献(References):

[1] Dongru D ,Guangyue Z ,Dan X , et al.Prevalence and clinical characteristics of sleep disorders in chronic obstructive pulmonary disease: A systematic review and meta-analysis.[J].Sleep medicine,2023,112282-290. 

[2]Marin M J ,Soriano B J ,Oto M M ,et al. Sleep-disordered Breathing in Patients with COPD: Prevalence and Outcomes. [J].Annals of the American Thoracic Society,2025, [3] Geng Y ,Hu Y ,Li B , et al. The Risk Factors and Predictors of Chronic Obstructive Pulmonary Disease in Patients With Obstructive Sleep Apnea-Hypopnea Syndrome at Plateau.[J].The clinical respiratory journal,2025,19(2):e70053. 

[4]彭利红,黄凤,陈莉莉,等.慢性阻塞性肺疾病患者睡眠障碍发生情况调查及其预测模型的建立[J].临床肺科杂志, 2025,30(02):176-182. 

[5]Bouloukaki I ,Christodoulakis A ,Margetaki K ,et al. The E in ff P e a c t t io en f t S s lew e i p th Im Ch p ra o in rm ic eO nt b, sta rsucA ts iv se esP su ed lm b o yn tah re y C D A isS e IaS seQ ou n e4 s] tioD nn isa e ira e s, e Severity and Physical and Mental Health: A Cross-Sectional Study in Primary Care[J].Biomedicines,2024,12(8):1644-1644. 

[6]Hansen K K ,Løkke A ,Jensen I H ,et al. Examining the i Cm O p P aD ct [ o J] f o .S b lse te ru p c a tin vd eB s r le e a e t p hin a g p, ne2 a02 on 4, co2 g 9 n( iti 1 v) e :f 5 u 9 n- c5 ti 9 o .n in severe 

[7]胡义萍,王芳,李迅,等.老年慢性阻塞性肺病患者睡眠障碍发生情况及与认知功能损害的相关性分析[J].现代生物医学进展,2024,24(17):3391-3395. 

[8] Saad Y A . Mental health and sleep quality among patients with asthma and COPD. [ J ] .Frontiers in medicine , 2023 , 101181742-1181742. 

[9] M L B ,W P S ,R E C , et al. Sleep problems and associations with cardiovascular disease and all-cause mortality in asthma-COPD overlap: analysis of the National Health and Nutrition Examination Survey (2007-2012).[J].Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine,2022,18(6). [10]Grassion L ,Patout M ,Wattiez N , et al. The interplay between sleep and neural respiratory drive in COPD: contribution of semi-automated analysis of long duration recordings[. J].NeuroImage, 2025,121445. 

[11]翁晓芹,张希龙,王文晶.阻塞性睡眠呼吸暂停与慢性阻塞性肺病及哮喘相关性的研究进展[J].国际老年医学杂志, 2024,45(06):717-722. 

[12] McNicholas T W . Does Obstructive Sleep Apnea Lead to Progression of Chronic Obstructive Pulmonary Disease [J].Sleep Medicine Clinics,2024,19(2):253-260. 

[13] Oto M M ,Rubio S D ,Marin M J . Obstructive Sleep Apnea and Chronic Obstructive Pulmonary Disease Overlap Syndrome.[J].Seminars in respiratory and critical care medicine, 2025.

[14] Yijia X ,Tianbao W ,Zhipeng M , et al. Auricular Acupuncture as a Traditional Chinese Medicine Therapy for Chronic Obstructive Pulmonary Disease Combined with Sleep Disorders. [J].Journal of visualized experiments : JoVE,2023,(198). 

[15]Wang H ,Liu L ,Wang C , et al.Acupoint Application Combined with Ear Plaster Therapy for Treating Sleep Disorders with Acute Exacerbation of Chronic Obstructive Pulmonary Disease. [J].Journal of visualized experiments: JoVE,2024,(212).

技术支持:人人站CMS
Powered by RRZCMS